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The North American Calorimetry Conference (CALCON) is the premier collegial forum for the dissemination of current research and state-of-the-art technologial developments in calorimetry and thermodynamics. Celebrating over seven decades of distinguished service to the scientific community since our inception in 1945, CALCON convenes annually at selected sites in the United States or Canada and jointly with the IUPAC sponsored International Conference on Chemical Thermodynamics whenever ICCT meets in North America. CALCON participants represent a broad cross-section of scientists in academia, government, and industry whose research interests span a diverse range of disciplines within the fields of biology, chemistry, physics, engineering, and emerging frontiers at the interface of core technologies.